Racks interchange
with Bio-eVap evaporators
Takahe manufactures SPE systems for both positive pressure and vacuum extraction — the speX Series for high-throughput pharmaceutical and CRO workflows, and vacuum manifolds for food testing, environmental, and water quality laboratories. Designed and manufactured in Navi Mumbai since 2015.
Solid Phase Extraction (SPE) is a chromatographic sample‑preparation technique that uses a solid sorbent to selectively isolate and concentrate target compounds from complex matrices. In a typical SPE method, either the analyte or the interfering matrix components are retained on the sorbent, then the retained analyte is eluted in a clean, concentrated fraction ready for GC, HPLC, or LC‑MS analysis. Takahe’s SPE systems implement this by driving solvent through the sorbent using either positive pressure or vacuum ( negative pressure).
When a BA/BE lab needs to process 48, 96, 144, or 210 samples in a single extraction run, the speX Series delivers consistent flow across every column, reproducible recoveries, and the IQ/OQ/PQ documentation trail required for regulatory submissions. Compressed nitrogen or instrument air drives extraction at a controlled, uniform rate — simultaneously across every position.
Primary applications: Pharmaceutical & API (BA/BE study prep) · Clinical research CRO (Phase I–IV) · High-throughput extraction prior to HPLC and LC-MS/MS.
144-position positive pressure SPE — split-rack design,
direct Bio-eVap compatibility, Phase IV scale
144 positions
Bio-eVap compatible
The speX 144 is built for Phase IV clinical studies and high-volume CRO operations where 144-sample runs are routine. Two problems arise at this scale that simply don’t exist at 48 or 96 positions — arm fatigue from managing one large rack, and errors in the transfer step from SPE to evaporation
The favourite, dependable and most popular SPE variant amongst CROs
Two problems at 144-position scale. Two Takahe solutions.
The 144 cartridge rack splits into three independent sections of 48. Visibility of eluting samples is identical to working on a speX 48. Each section is lighter on the arms, easier to handle, and loads flat on the benchtop without the risk of contaminating cartridge tips. Conceptualised, designed, and manufactured first by Takahe.
The speX 144 collection rack fits directly into Takahe's Bio-eVap 144 and 210 nitrogen evaporators. Move extracts from SPE to evaporation without any intermediate transfer — the rack goes straight in. No transfer errors, no lost samples, no additional handling time between steps.
Recently launched 210-position positive pressure SPE — India's highest-capacity manifold, complementing the Bio-eVap UHC 210
Recently launched
Highest capacity
matrix
The speX 210 is Takahe’s newest positive pressure SPE manifold — designed as a matched pair with the Bio-eVap UHC 210 to serve the scale of the largest Clinical Trial batches.
The highest-throughput positive pressure SPE system available from an Indian manufacturer.
Compact production model for pharma and research labs
Compact production
2 micro titre plates
Well-plate format SPE is the extraction workflow of choice in pharmaceutical discovery and high-throughput bioanalysis — wherever 96-well plate density, automation compatibility, and consistent recoveries in viscous biological matrices are all requirements. Positive nitrogen pressure drives uniform flow across all 192 wells in a single run, eliminating the well-to-well variability that vacuum manifolds introduce as individual wells progressively run dry.
The complimenting SPE system for labs using well-plates in their analysis
96-position positive pressure SPE — double the throughput, same racks, same operating procedure
Double throughput
No retraining
The speX 96 doubles the throughput of the speX 48 with no change to consumables, rack types, or operating procedure. Validated BA/BE methods transfer between the two models without retraining.
Built for BA/BE labs that consistently run two batches where a 48-position system would run one.
48-position positive pressure SPE — the compact production model for pharma and research labs
Compact production
12 kg
48 SPE cartridges processed simultaneously under positive nitrogen pressure. Interchangeable cartridge racks (1, 3, or 6 mL) and dual flow settings – max flow for conditioning and wash, rotameter-controlled for elution – keep every column at the same rate throughout the run.
The right model for pharmaceutical research labs and CROs running moderate-throughput SPE as part of a larger BA/BE workflow.
Specification | speX 48 | speX 96 | speX 144 | speX 210 | speX WP |
| Positions | 48 | 96 | 144 | 210 | Single or 2 Well Plate |
| Matrix | 4 × 12 | 8 × 12 | 12 × 12 | 15 × 14 | NA |
| Manifold Material | Anodised Aluminum | Anodised Aluminum | Anodised Aluminum | Anodised Aluminum | Anodised Aluminum |
| Rack Options for Cartridges | 1 / 3 / 6 mL | 1 / 3 / 6 mL | 1 / 3 mL | 1 mL | Micro Titre |
| Rack Options for Collection Tubes | 11.5 × 75 | 16 × 100 mm | 11.5 × 75 | 16 × 100 mm | 11.5 × 75 mm | 11.5 × 75 mm | NA |
| Flow Settings: Regulator Range | Max flow OR adjustable to 0–56 psi | Max flow OR adjustable to 0–56 psi | Max flow OR adjustable to 0–56 psi | Max flow OR adjustable to 0–56 psi | Max flow OR adjustable to 0–56 psi |
| Flow Settings: Rotameter Range | 0–10 SCFM | 0–15 SCFM | 0–15 SCFM | 0–15 SCFM | 0–10 SCFM |
| Waste Bin Inserts | 2 | 2 | 2 | 2 | NA |
| Dimensions (cm) | 49 × 30 × 45 | 49 × 48 × 45 | 49 × 68 × 45 | 49 × 68 × 45 | 49 × 30 × 45 |
| Weight | 12 kg | 18 kg | 34.5 kg | 34.5 kg | 10 kg |
| Documentation | DQ/IQ/OQ/PQ | DQ/IQ/OQ/PQ | DQ/IQ/OQ/PQ | DQ/IQ/OQ/PQ | DQ/IQ/OQ/PQ |
For food testing, environmental, and water-quality laboratories working with smaller sample batches, Takahe’s vacuum manifolds draw extraction solvents through SPE cartridges using controlled negative pressure. Available in 12 and 24 positions, with a choice of acrylic or chemical-resistant glass chamber and individual flow control at each port.
Primary applications: Food safety (honey, agro-products, pesticide residue) · Water quality · Soil and sediment testing · General SPE workflows with smaller batch sizes.
Compact benchtop vacuum extraction
Standard equipment for food and water testing labs
Benchtop
4 kg
Glass / Acrylic
The 12 / 24 position vacuum manifold processes all SPE cartridges simultaneously under controlled negative pressure. The transparent acrylic/glass chamber allows direct visual monitoring of solvent flow through each cartridge during conditioning, loading, washing, and elution. Each of the ports comes with an independent stopcock valve.
Note: The vacuum manifold requires a separate vacuum pump and vacuum trap, available on request. Contact Takahe for pump-selection guidance.
Specification | 12-position | 24-position |
|---|---|---|
| Positions | 12 | 24 |
| Extraction mode | Negative pressure | Negative pressure |
| Chamber material | Acrylic / Toughened glass | Acrylic / Toughened glass |
| Port flow control | Stopcock valve per port | Stopcock valve per port |
| Collection vessels | Tubes · flasks · vials | Tubes · flasks · vials |
| Dimensions (cm) | 35 × 12 × 27 | 40 × 13 × 30 |
| Weight | 4 kg | 7 kg |
| Vacuum Pump & Trap | Add available on request | Add available on request |
| Documentation | IQ/OQ/PQ | IQ/OQ/PQ |
| Model | Max samples | Max volume | Heating | Gas flow | Best for |
|---|---|---|---|---|---|
| SpeedoVap LV | 50 | 30 mL | Water bath | 150 LPM | Pharma, pesticide, clinical, food labs |
| SpeedoVap LX | 30 / 50 | 30 mL | Water bath | 90–150 LPM | Small labs, cost-sensitive budgets |
| Min-eVap (MV) | 15 | 15 mL | Water bath | 45 LPM | Education, food QC, low workload |
| SpeedoVap Dry Block | 15 | 15 mL | Dry heat block | 45 LPM | Contamination-sensitive, clinical, forensic |
BA/BE study sample preparation and high-throughput extraction prior to HPLC and LC-MS/MS in pharmaceutical QC and R&D.
speX 48 · 96 · 144 · 210
Phase I–IV trial sample processing at contract research organisations, with full DQ/IQ/OQ/PQ documentation for submissions.
speX 144 · 210
Honey, agro-products, and pesticide-residue extraction — the vacuum manifolds suit smaller food-safety batch sizes.
Vacuum 12 · 24
Drinking and process water, soil and sediment compliance testing using controlled negative-pressure extraction.
Vacuum 12 · 24
Positive pressure (the speX Series) uses compressed nitrogen or instrument air to push solvent through the cartridges at a controlled, uniform rate across every position — ideal for high-throughput, regulated BA/BE work. Vacuum manifolds pull solvent through using negative pressure, which suits smaller food, water, and environmental batches where individual per-port control and visual monitoring matter most.
At 144 positions, a single rack is heavy and tiring to handle. The speX 144 rack splits into three independent 48-sections — each lighter on the arms, easier to load flat on the bench, and with the same eluting-sample visibility as a speX 48. It was conceived, designed, and built first by Takahe.
Yes — the speX 144 collection rack fits Takahe’s Bio-eVap 100 and 144 evaporators, and the recently launched speX 210 pairs with the Bio-eVap UHC 210. Extracts move from SPE to evaporation with no intermediate transfer, removing transfer errors and saving handling time between steps.
The speX 210 is Takahe’s newest and highest-capacity positive pressure SPE manifold — 210 positions in a 15 × 14 matrix, launched to complement the Bio-eVap UHC 210 nitrogen evaporator. Together they form a matched 210-sample extraction-to-evaporation line for the largest Phase II and Phase IV clinical batches, with the same transfer-free rack workflow proven on the speX 144.
The speX Series ships with full DQ/IQ/OQ/PQ documentation; the vacuum manifolds ship with IQ/OQ/PQ. All models carry a one-year standard warranty with after-sales support from Takahe’s Navi Mumbai team.
Tell us your sample volumes, batch size, tube format, and application — our team will recommend the correct low volume model the same working day.
Spare and alternative-format cartridge racks (1 mL · 3 mL · 6 mL) let a single speX manifold switch between cartridge sizes, or keep a second rack pre-loaded to cut changeover time between batches.
Additional stainless-steel waste bins, waste-bin inserts, and interchangeable collection racks (10×75 · 12×75 · 16×100 mm) — to separate wash and conditioning fractions and adapt to different downstream vessels.
In a vacuum Manifold – the vacuum trap is a safety and protection device installed between the manifold and the vacuum source. Its purpose is to collect any liquid that is aspirated through the SPE tubes and prevent it from reaching the pump
The vacuum pump’s primary purpose is to create a controlled negative pressure (vacuum) that draws liquid samples through the SPE cartridges
